Essential Biochemistry - Enzymes (Section 1 - No. 38)
What is the effect of an irreversible inhibitor on an enzyme?
It binds non-covalently to the active site.
It permanently inactivates the enzyme.
It decreases the Km value.
It increases the Vmax value.
Explication
Irreversible inhibitors permanently inactivate an enzyme, usually through covalent modification.